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1.
JPAD-Journal of Pakistan Association of Dermatologists. 2011; 21 (4): 295-297
in English | IMEMR | ID: emr-118218

ABSTRACT

Lupus vulgaris is the most common form of cutaneous tuberculosis which usually occurs in patients previously sensitized to mycobacterium tuberculosis. It is often clinically and histopathologically confused with various cutaneous disorders. Here, we present a 28-year-old man attended in our medical college with slowly progressive, asymptomatic, annular erythematous skin lesions on the buttocks for 8 years. He consulted with many physicians and was improperly treated with an oral antifungal agent for several months under the diagnosis of tinea corporis, but no cure was observed. A diagnosis of lupus vulgaris was made based on the histopathological examination and the polymerase chain reaction. Anti-tuberculosis therapy was administered and the lesions started to regress


Subject(s)
Humans , Male , Adult , Lupus Vulgaris/pathology , Tinea/diagnosis , Buttocks/pathology , Polymerase Chain Reaction , Antitubercular Agents
2.
JPAD-Journal of Pakistan Association of Dermatologists. 2007; 17 (3): 166-170
in English | IMEMR | ID: emr-104651

ABSTRACT

Tinea capitis is caused by different species of dermatophytes particularly Microsporum and Trichophyton .Children are affected predominantly. Many systemic drugs e.g.griseofulvin, fluconazole, itraconazole, terbinafine, ketoconazoe etc are available for the treatment of tinea capitis. To compare the efficacy of griseofulvin and fluconazole in the treatment of tinea capitis. A total of 50 patients of age group 2-15 years were selected for the study.The cases were diagnosed clinically and confirmed by Wood 's lamp examination, KOH microscopy and culture.The patients were divided into two equal groups. Group A was given griseofulvin and group B was given fluconazole for a period of two months. Topical adjuvant therapy econazole nitrate was given in both groups. The patients were followed up at 2 weekly interval for clinical response and Wood 's lamp examination and finally KOH microscopy and culture. In group A clinical response was 84%and mycological response was 68%whereas in group B clinical response was 68%and mycological response was 56%. The present study showed that griseofulvin is more effective in the treatment of noninflammatory type of tinea capitis than fluconazole


Subject(s)
Humans , Male , Female , Griseofulvin , Fluconazole , Itraconazole , Microsporum/drug effects , Trichophyton/drug effects , Ketoconazole , Culture Techniques , Econazole , Microscopy
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